Tissue microarrays for high-throughput molecular pathology
نویسندگان
چکیده
منابع مشابه
Introducing tissue microarrays to molecular pathology.
Featured Article: Tissue microarrays for highthroughput molecular profiling of tumor specimens. Kononen J, Bubendorf L, Kallioniemi A, Bärlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallioniemi OP. Nat Med. 1998;4:844 –7. Tissue specimens are essential for biomedical and clinical research. In situ detection of DNA, RNA, and protein targets in tissues provides a powerful me...
متن کاملtissue microarrays, a revolution in pathology research
a long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. these two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and statistical thoroughness of tissue based studies. employing tissue microarray (tma) technique prov...
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Tissue microarray (TMA) technology allows rapid visualization of molecular targets in thousands of tissue specimens at a time, either at the DNA, RNA or protein level. The technique facilitates rapid translation of molecular discoveries to clinical applications. By revealing the cellular localization, prevalence and clinical significance of candidate genes, TMAs are ideally suitable for genomic...
متن کاملChange of Title: Microarrays Becomes High-Throughput
MDPI's journal Microarrays released its first volume in 2012. Since then, the journal has published 129 articles on the topic of microarrays, including their applications, analysis and new developments. [...].
متن کاملSoftware tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays.
The creation of tissue microarrays (TMAs) allows for the rapid immunohistochemical analysis of thousands of tissue samples, with numerous different antibodies per sample. This technical development has created a need for tools to aid in the analysis and archival storage of the large amounts of data generated. We have developed a comprehensive system for high-throughput analysis and storage of T...
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ژورنال
عنوان ژورنال: Annals of Saudi Medicine
سال: 2004
ISSN: 0256-4947,0975-4466
DOI: 10.5144/0256-4947.2004.169